Endocrine Abstracts

Background: Obesity and related co-morbidities have become an emerging major health concern in South Asia. In addition to the efficacy in weight control, bariatric surgery improves metabolic disorders, thus is a recognized mode of treatment in obesity.Objectives: To review the outcome of metabolic disorders in a group of obese patients in Sri Lanka following bariatric surgery.Methods: Patients who underwent bariatric surgery at Pro...

Using topical corticosteroids, severe adverse reactions occur very rarely, especially - adrenal insufficiency. We describe the case of a patient who presented adrenal insufficiency using topical GCC. 28 y/o female with a history of mild form psoriasis was treated with topical GCC (DERMOVATE) for about 12 years. Thinned skin, translucent vascular-network all over the body (~6 years), weight gain (+10 kg/12 months) and spontaneous haematomas appeared within the time and progress...

Introduction: Chromogranin A continues to be one of the most valuable markers for neuroendocrine tumors (NETs) however, it has several limitations, including its reduced specificity.Methods: The authors present the case of a patient diagnosed with a midgut NET, during follow-up.Results: Male patient, 61 years old, with chronic renal disease (CRD), underwent right hemicolectomy owing to ileo-cecal valve lesion; hist...

Objectives: Mean TBS (Trabecular Bone Score) values are generally lower in PHPT (primary hyperparathyroidism) patients than controls. The aim of this study was to assess TBS from spine DXA images in patients with PHPT and look at its correlates.Methods: This was a cross-sectional study conducted in an osteoporosis referral center. One hundred and thirty six patients with PHPT were selected from our database (2010–2016) if they had a valid LS DXA sca...

Introduction: Obstructive sleep apnea (OSA) affects up to 20% of a Western population and is associated with non-alcoholic fatty liver disease and type 2 diabetes (T2D). OSA is characterized by intermittent episodes of hypoxia (IH) that occur during sleep. It is not yet known if IH is directly linked to insulin resistance within key metabolic target tissues (adipose; liver and skeletal muscle) and what the potential underlying mechanism may be. It has been suggested that indiv...

Introduction: Pituitary incidentaloma (PitInc), defined as an unsuspected mass observed on imaging studies performed for unrelated conditions. Most such lesions are not clinically significant at initial evaluation and current guidelines recommend periodic follow-up.Aim: To present a rare case of delayed onset of acromegaly in a patient with a nonfunctioning PitInc, raising the question of the utility of prolonged follow-up of PitInc.<p class="abstext...

Hashimoto encephalopathy (HE) is a rare and steroid responsive encephalopathy associated with autoimmune thyroiditis (1). Patients with Hashimoto encephalopathy may present with a variety of neuropsychiatric signs (2). 68-year old woman was admitted to the Neurology Department, of Hospital of Lithuanian University of Health Sciences, Kauno klinikos (HLUHS KK), due to disorder of consciousness of uncertain aetiology in August 2016. The signs of motor dysfunction, generalized ri...

Despite that the thyroid gland is one of the most vascular organs of the body but thyroid gland is an uncommon site for metastasis [1]. It represents less than 4% of thyroid malignancy in clinical and surgical studies [2, 3]. 58-year-old male, a prior smoker, was diagnosed with nonsmall cell lung cancer T4N3M1 St IV, histopathological findings - infiltrative adenocarcinoma, G1. About eight months he was treated with chemotherapy. At the beginning of the disease, the patient wa...

An 18-year-old female presented to acute services with polydipsia and lower back pain. Routine blood tests revealed hypercalcaemia 3.67 mmol/l with significantly raised parathyroid hormone levels 2986 ng/l (10–65), alkaline phosphatase (ALP) 3330 IU/l (30–130), and low vitamin D 10.3 nmol/l (50–220). A CT scan revealed a 3.5 cm parathyroid adenoma and very osteopenic bones with multiple lucencies in keeping with primary hyperparathyoidism. The parathyroid subtra...

Introduction: Testicular regression syndrome (TRS) or vanishing testis syndrome is a rare condition defined as the absence of testicular tissue in a genetic and phenotypic male. Rudimentary accessory structures can be present; in that case, the removal of all remnants is recommended.Case report: Male patient, 39 years old, had initially been evaluated at the age of 8 for persistent bilateral cryptorchidism. The medical documents are lacking except for a ...